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R&D 100 Awards

Agilent Receives Prestigious R&D 100 Award for Technical Innovation PicoTRECT Opens New Avenues of Research for Atomic Force Microscopy (AFM) Recognized as One of the 100 Most Technologically Significant Products of the Year

Agilent is an R&D 100 Awards winner for its new PicoTREC. The awards are sponsored by R&D Magazine and recognize the top 100 products introduced into the marketplace during the year. PicoTREC is the only commercially available instrument to add real-time,， simultaneous Topography and RECognition imaging capability to the atomic force microscope (AFM). A breakthrough tool for AFM， PicoTREC allows researchers to pursue new avenues of discovery in all areas of nanotechnology and nanoscience.

PicoTREC,， used together with Agilent's 5 series® SPM (Scanning Probe Microscope) and MAC Mode®,， represents a new product category for AFM. PicoTREC improves the speed， sensitivity,， and accuracy of recognition and adhesion studies at the molecular level. Therefore,， it can be used to greatly accelerate existing research and to perform experiments that were not possible before. It is a label-less detection methodology so sensitive samples are not changed by the introduction of radioactive， fluorescent,， and other markers. Furthermore,， single molecule sensitivity is not only possible， with PicoTREC it is routine.

PicoTREC creates new possibilities for using AFM in life science,， materials science,， electrochemistry and other fields. For example， PicoTREC offers researchers in cell biology,， nanobiotechnology and pharmacology the ability to explore dynamic properties of molecular binding events. It enables studies on a host of ligand-receptor interactions including membranes,， cells， antibody-antigen,， drug-receptor,， DNA-protein， DNA-DNA,， and smart materials. In addition,， for scientists studying the characteristics of data storage media including CD's， DVD's and hard drives,， or sensors,， polymers and other materials， PicoTREC provides a better understanding of the molecular level structures and interactions that influence their behaviors.

Picotrec獲得美國R&D 100 Awards 大獎,！

主要特點：

安捷倫的PicoTREC分子識別功能能應(yīng)用到我們每個AFM型號中,，它通過探測兩種物質(zhì)的分子鍵是否發(fā)生相互結(jié)合，來快速識別感興趣的官能團(tuán),，輕松取代其它供貨商的那些雖可獲得同樣結(jié)果,，但卻既耗時又操作復(fù)雜，且只能借助力譜測量等分析的功能塊,。生物活體成像模式與PicoTREC結(jié)合使用,，通過分析分子鍵和表面的吸附力，你可研究生物系統(tǒng)的動態(tài)性質(zhì),，包括抗體—抗原,、配體—受體,、藥物－受體、DNA—蛋白質(zhì),、DNA—DNA等等,。

概述

簡便快速的識別出分子結(jié)合事件中的分子或發(fā)生區(qū)域

通過結(jié)合相互作用來示出物質(zhì)的種類

給出樣品表面的吸附性的分布

提高得結(jié)果的速度、準(zhǔn)度和精度

通過確定分子作用區(qū)來加速力測試

圖示出分子的排列

儀器特點

無標(biāo)記監(jiān)測分子結(jié)合事件

同時獲取形貌像和分子識別像

實時監(jiān)測樣品表面的結(jié)合事件和粘附性能

與安捷倫科技的生物活體成像模式和5500系列完全兼容

應(yīng)用領(lǐng)域：

1,、探索生物領(lǐng)域的動態(tài)性能(抗體-抗原,，配體-受體， 藥物-受體,， DNA-蛋白質(zhì),， DNA-DNA 等)，分子結(jié)合研究:

2,、排列檢測應(yīng)用

3,、顯示表面分子結(jié)合事件和粘附性的狀況

4、更多需要探索的未知領(lǐng)域