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爪腫測(cè)量?jī)x儀器簡(jiǎn)介:
爪腫測(cè)量?jī)x計(jì)用于測(cè)量抗腫藥物的效果.爪腫測(cè)量?jī)x使用方法簡(jiǎn)單,將腫脹的大鼠爪放入儀器的水槽中,,導(dǎo)致水平面上升,,爪腫測(cè)量?jī)x測(cè)量出水平面上升引起的水壓力變化值,該壓力變化值對(duì)應(yīng)伸入水中腫脹大鼠爪的體積,;
爪腫測(cè)量?jī)x 的詳細(xì)介紹
產(chǎn)品品牌:意大利UGO 產(chǎn)品型號(hào):37140 爪腫測(cè)量?jī)x設(shè)計(jì)用于風(fēng)濕關(guān)節(jié)炎,、水腫、藥理作用等研究,,精確測(cè)量嚙齒類動(dòng)物肢體的腫脹情況,。自上世紀(jì)60年代起,已經(jīng)有超過1000篇的引文,。該儀器是大,、小鼠炎癥水腫測(cè)量的理想工具,其測(cè)量分辨率是0.01ml,。 爪腫測(cè)量?jī)x整套儀器包含一個(gè)腳踏開關(guān),,用于記錄讀數(shù),從而使得操作人員可以全神貫注于將動(dòng)物的爪侵沒于測(cè)量水杯中,。液晶屏實(shí)時(shí)顯示實(shí)驗(yàn)數(shù)據(jù),,通過相應(yīng)軟件可方便的將實(shí)驗(yàn)數(shù)據(jù)導(dǎo)入電腦。 爪腫測(cè)量?jī)x使用方法簡(jiǎn)單,,將腫脹的大鼠爪放入儀器的水槽中,,導(dǎo)致水平面上升,爪腫測(cè)量?jī)x測(cè)量出水平面上升引起的水壓力變化值,,該壓力變化值對(duì)應(yīng)伸入水中腫脹大鼠爪的體積,;對(duì)大鼠服用抗腫脹藥物,大鼠的爪相應(yīng)消腫,,將消腫的大鼠爪放入水槽中,,導(dǎo)致水平面上升,爪腫測(cè)量?jī)x測(cè)量出水平面上升引起的水壓力變化值,,該壓力變化值對(duì)應(yīng)伸入水中消腫大鼠爪的體積,,根據(jù)兩次水壓力變化值即體積的差值評(píng)估得出抗腫脹藥物的效果。 特征 腳踏記錄實(shí)驗(yàn)數(shù)據(jù) 超過1000引文 多測(cè)量水杯可選 優(yōu)點(diǎn) 免手持操作 絕大多數(shù)應(yīng)用開在參考文獻(xiàn)中查到 可用于大,、小鼠實(shí)驗(yàn) 規(guī)格參數(shù): 測(cè)量水杯直徑:1.3 cm (小鼠),, 1.8; 2.5 & 3.5 cm (大鼠) 讀數(shù)分別率:0.01ml 與電腦連接:串行接口或USB接口 軟件:包含在標(biāo)配中 參考文獻(xiàn): et alia: “A2A Adenosine Receptors Are Differentially Modulated by Pharmacological Treatments in Rheumatoid Arthritis Patients and Their Stimulation Ameliorates Adjuvant-Induced Arthritis in Rats” PLoS ONE 8(1): e54195,, 2013 § T. Bertaim et alia: “Dose and Administration Schedule Effect of Tiludronate on Joint Damage in the Model of Complete Freund Adjuvant Induced Monoarthritis in Rats” Open Journal of Rheumatology and Autoimmune Diseases 3: 18-25, 2013 § E. Borbély et alia: “Role of Tachykinin 1 and 4 Gene-Derived Neuropeptides and the Neurokinin 1Receptor in Adjuvant-Induced Chronic Arthritis of the Mouse” PLoS ONE 8(4): e61684,,2013 ...... § R. Korhonen et alia: “Attenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated by MAPK phosphatase-1” Br. J. Pharmacol. 169 (7):1525-1536,, 2013
§ A. Finlay et alia: “Sphingosine 1-Phosphate Mediates Hyperalgesia via a Neutrophil-Dependent Mechanism” PLoS ONE 8(1): e55255, 2013.....
§ D. Piomelli et alia:” Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism”. Nature NSC,, 2010
§ L.H. Santos et alia: "Anti-Inflammatory,, antinociceptive and Ulcerogenic Activity of a Zinc-Diclofenac Complex in Rats" Brazil. J. Med. Biol. Res. 37: 1205-1213, 2004
§ D.W. Li et alia: "Antiinflammatory Activity of a α-Hederin methyl Ester from the Alkaline Hydrolysate of the Butanol Fraction of Kalopanax Pictus Bark Extract" Biol. Pharm. Bull. 26 (4): 429-433,, 2003
§ A. Rotelli et alia: “Comparative Study of Flavonoids in Experimental Models of Inflammation” Pharmacol. Research 48: 601-606,, 2003
§ H. Machelska et alia: "Opioid Control of Inflammatory Pain Regulated by Intercellular Adhesion Molecule-1" J. Neuroscience 22 (13), 5588-5596,, 2002
§ W. Binder & J. Walker: "Effect of the Peripherally Selective Κ-Opioid Agonist,, Asimadoline, on Adjuvant Arthritis" Br. J. Pharmacol. 124: 647-654,, 1998
§F. Vincenzi
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